MNMS > Publications

Publications

Oncology

Contribuables: MA Abu el Maaty, J Terzic, C Keime, D Rovito, R Lutzing, D Yanushko, M Parisotto, E Grelet, IJ Namer, V Lindner, G Laverny, D Metzger.

Hypoxia-mediated stabilization of HIF1a in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression.

Science Advances 8: eabo2295, 2022. 192_HRMAS_Metzger

Contribuables: D Cakmakci, G Kaynar, C Bund, M Piotto, F Proust, IJ Namer, AE Cicek

Targeted metabolomics analyses for brain tumor marging assessment during surgery

Bioinformatics 38: 3238-3244, 2022. 189_HRMAS_ExtempoRMN

Contribuables: TN Chamaroux-Tran, M Muller, J Pottecher, PA Diemunsch, C Tomasetto, IJ Namer, N Dali-Youcef

Metabolomic impact of lidocaine on a triple negative breast cancer cell line

Frontiers in Pharmacology 13: 1-10, 2022. 187_HRMAS_Lidocaine

Contribuables: D Cakmakci, EO Karakaslar, E Ruhland, MP Chenard, F Proust, M Piotto, IJ Namer, AE Cicek.

Machine learning assisted intraoperative assessment of brain tumor margins using HRMAS NMR spectroscopy

PLoS Computational Biology 16: e1008184, 2020. 176_HRMAS_ExtempoRMN

Contribuables: L Bender, F Somme, E Ruhland, AE Cicek, C Bund, IJ Namer

Metabolomics profile of aggressive meningiomas by using high-resolution magic angle spinning nuclear magnetic resonance

Journal of Proteome Research 19: 292-299, 2020. 172_HRMAS_MEN

Contribuables: A Imperiale, G Poncet, P Addeo, E Ruhland, C Roche, S Battini, AE Cicek, MP Chenard, V Hervieu, B Goichot, P Bachellier, T Walter, IJ Namer

Metabolomics of small intestine neuroendocrine tumors and related hepatic metastases

Metabolites 9: 300, 2019. 171_HRMAS_TNI

Contribuables: AF Blandin, A Durand, M Litzler, A Tripp, E Guérin, E Ruhland, A Obrecht, C Keime, Q Fuchs, D Reita, B Lhermitte, A Coca, C Jones, I Lelong-Rebel, P Villa, IJ Namer, M Dontenwill, D Guenot, N Entz-Werle.

Hypoxic environment and paired hierarchical 3D and 2D models of pediatric H3.3 mutated gliomas recreate the patient tumor complexity

Cancers 11: 1875, 2019. 170_HRMAS_PedGlioma

Contribuables: C Bund, B Lhermitte, AE Cicek, E Ruhland, F Proust, IJ Namer.

What does reduced FDG uptake mean in high-grade gliomas?

Clinical Nuclear Medicine 44: 936-942, 2019. 166_HRMAS_Glioma_FDG

Contribuables: C Bund, M Guergova-Kuras, AE Cicek, FM Moussallieh, N Dali-Youcef, M Piotto, P Schneider, N Entz-Werle, B Lhermitte, MP Chenard, R Schott, F Proust, G Noël, IJ Namer

An integrated genomics and metabolomics approach for defining survival time in adult oligodendrogliomas patients.

Metabolomics 15:69, 2019. 161_HRMAS_Oligo3

Contribuables: S Hescot, L Amazit, M Lhomme, S Travers, A DuBow, S Battini, IJ Namer, A Lombès, A Kontush, A Imperiale, E Baudin, M Lombès

Identifying mitotane-induced mitochondria-associated membranes dysfunctions: Metabolomic and lipidomic approaches

Oncotarget 8: 109924-109940, 2017. 146_HRMAS_MAM

Contribuables: A Nguyen, FM Moussallieh, A MacKay, AE Ciçek, A Coca, MP Chenard, N Weingertner, E Letouzé, E Guerin, E Pencreach, C Lasthaus, S Jannier, D Guenot, IJ Namer, J Chris, N Entz-Werle

Characterization of transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1a axis inhibition

Oncotarget 8: 71597-71617, 2017. 144_HRMAS_Nguyen

Contribuables: AE Abdullah, C Guerin, A Imperiale, A Barlier, S Battini, M Pertuit, P Roche, W Essamet, B Vaisse, K Pacak, F Sebag, D Taïeb

Paraganglioma of the organ of Zuckerkandl associated with a somatic HIF2α mutation: A case report

Oncology Letters 13: 1083-1086, 2017. ol-13-03-1083

Contribuables: S Battini, F Faitot, A Imperiale, AE Çiçek, C Heimburger, G Averous, P Bachellier, IJ Namer

Metabolomics approach in pancreatic adenocarcinoma: tumor metabolism predicts clinical outcome of patients

BMC Medicine 15: 56, 2017. 143_HRMAS_BMC http://www.cnrs.fr/insis/recherche/actualites/2017/06/cancer-pancreas.html

Contribuables: S Battini, A Imperiale, D Taieb, K Elbayed, A.E Cicek, F Sebag, L Brunaud, IJ Namer

High-Resolution Magic Angle Spinning 1H Nuclear Magnetic Resonance Spectroscopy Metabolomics of hyperfunctioning parathyroid glands

Surgery 160: 384-394, 2016

Contribuables: A Imperiale, S Battini, G Averous, D Mutter, B Goichot, P Bachellier, K Pacak, D Taïeb, IJ Namer

In vivo detection of catecholamines by magnetic resonance spectroscopy: A potential specific biomarker for diagnosis of pheochromocytoma

Surgery 159: 1231-1233, 2016.

Contribuables: A Varoquaux, Y Le Fur, A Imperiale, A Reyre, M Montava, N Fakhry, IJ Namer, G Moulin, K Pacak, M Guye, D Taïeb

Magnetic resonance spectroscopy of paragangliomas: new insights into in vivo metabolomics

Endocrine-Related Cancer 22: M1-M8, 2015.

Contribuables: E Szarek, ER Ball, A Imperiale, M Tsokos, FR Faucz, A Giubellino, FM Moussallieh, IJ Namer, MS Abu-Asab, K Pacak, D Taïeb, A Carney, CA Stratakis

Carney Triad, SDH-deficient tumors, and Sdhb+/- mice share abnormal mitochondria

Endocrine-Related Cancer 22: 345-352, 2015.

Contribuables: N Dali-Youcef, S Froelich, FM Moussallieh, S Chibbaro, G Noël, IJ Namer, S Heikkinen, J Auwerx

Gene expression mapping of histone deacetylases and co-factors and correlation with survival time and 1H-HRMAS metabolomics profile in human gliomas

Scientific Reports 5: 9087, 2015.

Contribuables: A Imperiale, FM Moussallieh, P Roche, S Battini, E Cicek, F Sebag, L Brunaud, A Barlier, K Elbayed, A Loundou, P Bachellier, B Goichot, CA Stratakis, K Pacak, , IJ Namer, D Taïeb

Metabolome profiling by HRMAS NMR spectroscopy of pheochromocytomas and paragangliomas detects SDH deficiency: Clinical and pathophysiological implications

Neoplasia 17:55-65, 2015.

Contribuables: A Imperiale, FM Moussallieh, F Sebag, L Brunaud, A Barlier, K Elbayed, P Bachellier, B Goichot, K Pacak, IJ Namer, D Taïeb

A new specific succinate-glutamate metabolomic hallmark in Sdhx-related paragangliomas

PLoS One 8: e80539, 2013.

Contribuables: A Imperiale, K Elbayed, FM Moussallieh, N Reix, M Piotto, B Goichot, P Bachellier, JP Bellocq, IJ Namer

Metabolomic profile of the adrenal gland: from physiology to pathologic conditions

Endocrine-Related Cancer 20: 705-716, 2013.

Contribuables: M Piotto, FM Moussallieh, A Neuville, JP Bellocq, K Elbayed, IJ Namer

Towards real-time metabolic profiling of biopsy specimen during a surgical operation by 1H HRMAS-NMR: A case report

Journal of Medical Case Reports 6: 22, 2012.

Contribuables: A Imperiale, K Elbayed, FM Moussallieh, A Neuville, M Piotto, JP Bellocq, P Lutz, IJ Namer

Metabolomic pattern of childhood neuroblastoma obtained by 1H-High-Resolution Magic Angle Spinning (HRMAS) NMR spectroscopy

Pediatric Blood & Cancer 56: 24-34, 2011.

Contribuables: M Piotto, FM Moussallieh, B Dillmann, A Imperiale, A Neuville, C Brigand, JP Bellocq, K Elbayed, IJ Namer

Metabolic characterization of primary human colorectal cancers using high-resolution magic angle spinning 1H magnetic resonance spectroscopy

Metabolomics 5: 292-301, 2009.

Contribuables: G Erb, K Elbayed, M Piotto, J Raya, A Neuville, M Mohr, D Maitrot, P Kehrli, IJ Namer

Towards improved grading of malignancy in oligodendrogliomas using metabolomics

Magnetic Resonance in Medicine 59: 959-965, 2008.

Off-oncology

Contribuables: F Marchegiani, E Noll, P Riva, SH Kong, P Saccomandi, G Vita, V Linder, IJ Namer, J Marescaux, P Diemunsch, M Diana

Effects of warmed and humidified CO2 surgical site insufflation in a novel experimental model of magnetic compression colonic anastomosis.

Surgical Endoscopy 28: 7-17, 2021. 179_HRMAS_Marchegiani

Contribuables: M Wurtz, E Ruhland, X Liu, IJ Namer, D Lipsker, V Mazzoleni, D Keller, G Prévost, D Gaucher

Panton-Valentine Leukocidin of Staphylococcus aureus induces oxidative stress and neurotransmitter imbalance in a retinal explant model.

Investigative Ophthalmology & Visual Science 62: 4, 2021. 180_HRMAS_Wurtz

Contribuables: F Faitot, E Ruhland, C Oncioiu, C Besch, P Addeo, AE Cicek, P Bachellier, IJ Namer.

Metabolomic profiling highlights the metabolic bases of acute-on-chronic and post-hepatectomy liver failure

HPB, 21: 1354-1361, 2019. 163_HRMAS_HBP

Contribuables: J Detour, C Bund, C Behr, H Cebula, AE Cicek, MP Valenti-Hirsch, B Lannes, B Lhermitte, A Nehlig, P Kehrli, F Proust, IJ Namer

Metabolomic characterization of human hippocampus from drug-resistant epilepsy with mesial temporal seizure.

Epilepsia 59:607-616, 2018. 154_HRMAS_EPI

Contribuables: S Battini, C Bund, FM Moussallieh, AE Ciçek, J De Sèze, IJ Namer

Metabolomics approaches in experimental allergic encephalomyelitis.

Journal of Neuroimmunology 314: 94-100, 2018. 153_HRMAS_EAE

Contribuables: F Faitot, S Battini, C Besch, E Ruhland, M Onea, P Addeo, ML Woehl-Jaeglé, B Ellero, P Bachellier, IJ Namer

Impact of real-time metabolomics in liver transplantation: graft evaluation and donor-recipient matching.

Journal of Hepatology 68: 699-706, 2017. 149_HRMAS_JHepatol

Contribuables: Noll E, Diana M, Charles AL, Singh F, Gan TJ, Pottecher J, Moussallieh FM, Namer IJ, Geny B, Diemunsch P.

Comparative analysis of resuscitation using human serum albumin and crystalloids or 130/0.4 hydroxyethyl starch and crystalloids on skeletal muscle metabolic profile during experimental haemorrhagic shock in swine: A randomised experimental study

European Journal of Anaesthesiology 34: 89-97, 2017. 137_HRMAS_Noll

Contribuables: Vivot, MA Benahmed, E Seyfritz, W Bietiger, K Elbayed, E Ruhland, A Langlois, E Maillard, M Pinget, N Jeandidier, JP Gies, IJ Namer, S Sigrist, N Reix.

A metabolomic approach (1H HRMAS NMR spectroscopy) supported by histology to study early post-transplantation responses in islet-transplanted livers

International Journal of Biological Sciences 12: 1168-1180, 2016. 135_HRMAS_Reix

Contribuables: E Moss, C Debeuckelaere, V Berl, K Elbayed, FM Moussallieh, IJ Namer, JP Lepoittevin

In situ metabolism of cinnamyl alcohol in reconstructed human epidermis: new insights into the activation of this fragrance skin sensitizer

Chemical Research in Toxicology 29: 1172-1178, 2016. 134_HRMAS_peau4

Contribuables: C Debeuckelaere, FM Moussallieh, K Elbayed, IJ Namer, V Berl, E Gimenez, JP Lepoittevin

In situ chemical behavior of methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) in reconstructed human epidermis: a new approach to the cross-reactivity issue

Contact Dermatitis 74: 159-167, 2016.

Contribuables: C Debeuckelaere, V Berl, K Elbayed, FM Moussallieh, IJ Namer, JP Lepoittevin

Matrix effect of human reconstructed epidermis on the chemoselectivity of skin sensitizing α-methylene-γ-butyrolactone: consequences for development of in chemico alternative methods.

Chemical Research in Toxicology 28: 2192-2198, 2015.

Contribuables: M Diana, E Noll, P Diemunch, FM Moussallieh, IJ Namer, AL Charles, V Lindler, V Agnus, B Geny, J Marescaux

Metabolism guided bowel resection: potential role and accuracy of instant capillary lactates to identify the optimal resection site

Surgical Innovation 22: 453-461, 2015.

Contribuables: MA Benahmed, K Elbayed, F Daubeuf, N Santelmo, N Frossard, IJ Namer

NMR HRMAS spectroscopy of lung biopsy samples: Comparaison study between human, pig, rat and mouse metabolomics

Magnetic Resonance in Medicine 71: 35-43, 2014.

Contribuables: M Diana, E Noll, P Diemunch, B Dallemagne, MA Benahmed, V Agnus, L Soler, B Barry, IJ Namer, N Demartines, AL Charles, B Geny, J Marescaux

Enhanced-reality video-fluorescence to assess the intestinal viability

Annals of Surgery 259: 700-707, 2014.

Contribuables: FM Moussallieh, K Elbayed, JB Chanson, G Rudolf, M Piotto, J de Sèze, IJ Namer

Serum metabolomics by 1H nuclear magnetic resonance spectroscopy: a new tool for distinguishing for distinhuishing neuromyelitis optica from multiple sclerosis

Multiple Sclerosis Journal 20: 558-565, 2014.

Contribuables: K Elbayed, V Berl, C Debeuckelae, FM Moussallieh, M Piotto, IJ Namer, JP Lepoittevin

HR-MAS NMR spectroscopy of reconstructed human epidermis: Potential for the in situ investigation of chemical interactions of skin allergens with nucleophilic amino acids

Chemical Research in Toxicology 26: 136-145, 2013.

Contribuables: D Gaucher, E Arnault, Z Husson, N Froger, E Dubus, P Gondouin, D Dherbécourt, J Degardin, M Simonutti, S Fouquet, MA Benahmed, K Elbayed, IJ Namer, P Massin, JA Sahel, S Picaud

Taurine deficiency damages retinal neurones : Cone photoreceptors and retinal ganglion cells

Amino Acids 43:1979-1993, 2012.

Contribuables: MA Benahmed, N Santelmo, K Elbayed, E Noll, N Frossard, M Canuet, P Diemunsch, M Piotto, G Massard, IJ Namer

The assessment of the quality of the graft in an animal model for lung transplantation using the metabolomics 1H high-resolution magic angle spinning NMR spectroscopy

Magnetic Resonance in Medicine 68: 1026-1038, 2012.

Contribuables: J Detour, K Elbayed, FM Moussallieh, M Piotto, A Nehlig, IJ Namer

Ultra fast in vivo microwave irradiation for enhanced metabolic stability of brain biopsy samples during HRMAS NMR analysis

HRMAS NMR analysis. Journal of Neuroscience Methods 201: 89-97, 2011.

Methodology

Contribuables: H Outilaft, C Bund, M Piotto, IJ Namer.

Analysis of metabolic pathways by 13C-labelled molecular probes and HRMAS NMR spectroscopy: Isotopologues identification and quantification methods for medical applications.

Analytical Chemistry 94: 8226-8233, 2022. 188_HRMAS_C13 188_HRMAS_C13supl

Contribuables: D Cakmakci, G Kaynar, C Bund, M Piotto, F Proust, IJ Namer, AE Cicek

Targeted metabolomics analyses for brain tumor marging assessment during surgery

Bioinformatics 38: 3238-3244, 2022. 189_HRMAS_ExtempoRMN

Contribuables: D Cakmakci, EO Karakaslar, E Ruhland, MP Chenard, F Proust, M Piotto, IJ Namer, AE Cicek.

Machine learning assisted intraoperative assessment of brain tumor margins using HRMAS NMR spectroscopy

PLoS Computational Biology 16: e1008184, 2020. 176_HRMAS_ExtempoRMN

Contribuables: EO Karakaslar, B Coskun, H Outilaft, IJ Namer, AE Cicek.

Predicting carbon spectrum in heteronuclear single quantum coherence spectroscopy for online feedback during surgery

IEEE/ACM Transactions on Computational Biology and Bioinformatics 17: 719-725, 2020. 171_HRMAS_IEEE

Contribuables: E Ruhland, C Bund, H Outilaft, M Piotto, IJ Namer.

A metabolic database for biomedical studies of biopsy specimens by high-resolution magic angle spinning nuclear MR: A qualitative and quantitative tool.

Magnetic Resonance in Medicine 82: 62-83, 2019. 160_HRMAS_Database

Contribuables: A Agin, D Heintz, E Ruhland, JM Chao de la Barca, J Zumsteg, V Moal, AS Gauchez, IJ Namer

Metabolomics – an overview: From basic principles to potential biomarkers (part 1)

Médecine Nucléaire 40: 4-10, 2016.

Contribuables: F Bertrand, N Meyer, M Beau-Faller, K Elbayed, IJ Namer, M Maumy-Bertrand

Régression Bêta PLS

Journal de la Société Française de Statistique 154: 143-159, 2013.

Contribuables: M Piotto, FM Moussallieh, A Imperiale, MA Benahmed, J Detour, JP Bellocq, IJ Namer, K Elbayed

Reproducible sample preparation and spectrum acquisition techniques for metabolic profiling of human tissues by proton high-resolution magic angle spinning nuclear magnetic resonance

In « Methodologies in metabolomics : Experimental strategies and techniques for metabolomics research » (Ed. P Lutz), Cambridge University Press, pp. 496-524, 2012.